Application of MALDI-TOF mass spectrometry for the diagnosis and monitoring of patients with multiple myeloma.

Cristina Agullo Roca

Centro de Investigación del Cáncer (CSIC-USAL), Hospital Universitario de Salamanca

Date: 06/02/2025

Time: 12:30

CIC Hall Lecture

Host: María-Victoria Mateos

In this session we will learn about MALDI-TOF mass spectrometry technology applied to the detection, characterisation and quantification of monoclonal protein in patients with multiple myeloma.

The main objectives are:
1) To compare the ability to detect monoclonal protein in serum samples from patients with multiple myeloma by MALDI-TOF mass spectrometry and by conventional methods (SPE/IFE) used in laboratories.

2) To investigate the clinical value, in terms of progression-free survival, of the results obtained by EPS/IFE and MALDI-TOF mass spectrometry in serum samples and by new generation flow cytometry in bone marrow samples, during treatment monitoring.